{"id":5641,"date":"2024-03-06T15:31:50","date_gmt":"2024-03-06T08:31:50","guid":{"rendered":"https:\/\/jhasim1.com\/?p=5641"},"modified":"2024-03-06T15:31:50","modified_gmt":"2024-03-06T08:31:50","slug":"nhung-thuoc-moi-ket-hop-hoat-chat-trong-dieu-tri-tang-huyet-ap","status":"publish","type":"post","link":"https:\/\/jhasim1.com\/nhung-thuoc-moi-ket-hop-hoat-chat-trong-dieu-tri-tang-huyet-ap.html","title":{"rendered":"Nh\u1eefng thu\u1ed1c m\u1edbi k\u1ebft h\u1ee3p ho\u1ea1t ch\u1ea5t trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p"},"content":{"rendered":"

Trong c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00fd t\u0103ng huy\u1ebft \u00e1p (THA) hi\u1ec7n nay, vi\u1ec7c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t \u0111\u01b0\u1ee3c c\u00e1c th\u1ea7y thu\u1ed1c r\u1ea5t hay s\u1eed d\u1ee5ng. M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n khi d\u00f9ng \u0111\u01a1n l\u1ebb m\u1ed9t thu\u1ed1c huy\u1ebft \u00e1p th\u01b0\u1eddng kh\u00f3 duy tr\u00ec \u0111\u01b0\u1ee3c m\u1ee9c huy\u1ebft \u00e1p m\u1ee5c ti\u00eau. V\u00ec v\u1eady, \u00e1p d\u1ee5ng ph\u00e1c \u0111\u1ed3 ph\u1ed1i h\u1ee3p thu\u1ed1c trong \u0111i\u1ec1u tr\u1ecb THA \u0111\u00e3 tr\u1edf n\u00ean ng\u00e0y c\u00e0ng th\u00f4ng d\u1ee5ng nh\u1eb1m \u0111\u1ea1t \u0111\u01b0\u1ee3c tr\u1ecb s\u1ed1 huy\u1ebft \u00e1p mong mu\u1ed1n cho ng\u01b0\u1eddi b\u1ec7nh \u0111\u1ed3ng th\u1eddi gi\u00fap b\u1ea3o v\u1ec7 m\u1ea1ch m\u00e1u n\u00e3o, th\u1eadn v\u00e0 tim.<\/p>\n

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S\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb T\u0103ng huy\u1ebft \u00e1p c\u1ea7n h\u1ebft s\u1ee9c th\u1eadn tr\u1ecdng<\/figcaption><\/figure>\n

\u0110\u1ec3 gi\u00fap cho ng\u01b0\u1eddi b\u1ec7nh b\u1ecb THA kh\u00f4ng ph\u1ea3i d\u00f9ng \u0111\u1ed3ng th\u1eddi 2-3 ho\u1eb7c 4 thu\u1ed1c v\u1edbi c\u00e1c ho\u1ea1t ch\u1ea5t \u0111\u01a1n l\u1ebb c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p \u0111\u1ebfn m\u1ee9c c\u1ea7n duy tr\u00ec, c\u00e1c nh\u00e0 b\u00e0o ch\u1ebf d\u01b0\u1ee3c ph\u1ea9m \u0111\u00e3 \u0111\u01b0a ra th\u1ecb tr\u01b0\u1eddng kh\u00e1 nhi\u1ec1u d\u1ea1ng thu\u1ed1c m\u00e0 trong m\u1ed7i vi\u00ean thu\u1ed1c \u0111\u00e3 ph\u1ed1i h\u1ee3p nhi\u1ec1u ho\u1ea1t ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p, duy tr\u00ec m\u1ee9c huy\u1ebft \u00e1p an to\u00e0n cho ng\u01b0\u1eddi b\u1ec7nh. V\u00ec v\u1eady, hi\u1ec7n nay c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb THA v\u1edbi th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t ph\u1ed1i h\u1ee3p 2 ho\u1eb7c 3 ch\u1ea5t kh\u00e1c nhau l\u00e0 r\u1ea5t ph\u1ed5 bi\u1ebfn. Ng\u01b0\u1eddi d\u00f9ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb THA c\u1ea7n bi\u1ebft \u0111\u1eb7c t\u00ednh c\u1ee7a thu\u1ed1c m\u00ecnh \u0111ang s\u1eed d\u1ee5ng \u0111\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi th\u1ea7y thu\u1ed1c l\u1ef1a ch\u1ecdn d\u1ea1ng b\u00e0o ch\u1ebf ph\u00f9 h\u1ee3p v\u1edbi m\u1ed7i c\u00e1 th\u1ec3.<\/p>\n

Vi\u1ec7c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t trong m\u1ed9t vi\u00ean thu\u1ed1c mang l\u1ea1i hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p t\u1ed1t h\u01a1n v\u00e0 gi\u1ea3m nguy c\u01a1 b\u1ec7nh l\u00fd kh\u00e1c cao h\u01a1n so v\u1edbi vi\u1ec7c t\u0103ng li\u1ec1u d\u00f9ng c\u1ee7a m\u1ed9t thu\u1ed1c ch\u1ec9 c\u00f3 m\u1ed9t ho\u1ea1t ch\u1ea5t. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u cho th\u1ea5y vi\u1ec7c ph\u1ed1i h\u1ee3p 2 ho\u1ea1t ch\u1ea5t t\u01b0\u01a1ng h\u1ee3p hi\u1ec7p \u0111\u1ed3ng c\u1ed9ng trong m\u1ed9t thu\u1ed1c gi\u00fap l\u00e0m gi\u1ea3m huy\u1ebft \u00e1p nhi\u1ec1u h\u01a1n \u0111\u1ebfn 5 l\u1ea7n so v\u1edbi vi\u1ec7c t\u0103ng g\u1ea5p \u0111\u00f4i li\u1ec1u c\u1ee7a thu\u1ed1c ch\u1ec9 c\u00f3 m\u1ed9t ho\u1ea1t ch\u1ea5t. Ngo\u00e0i ra, l\u1ee3i \u00edch c\u1ee7a \u0111i\u1ec1u tr\u1ecb THA \u0111a ho\u1ea1t ch\u1ea5t gi\u00fap t\u0103ng hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p, gi\u1ea3m t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c, c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n \u0111\u1ed9 dung n\u1ea1p c\u1ee7a b\u1ec7nh nh\u00e2n, gi\u1ea3m bi\u1ebfn c\u1ed1 tim m\u1ea1ch v\u00e0 t\u1eed vong do bi\u1ebfn c\u1ed1 \u0111\u00f3.<\/p>\n

M\u1ed9t s\u1ed1 d\u1ea1ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb THA ph\u1ed1i h\u1ee3p ph\u1ed5 bi\u1ebfn hi\u1ec7n nay hay c\u00f3 tr\u00ean th\u1ecb tr\u01b0\u1eddng l\u00e0 thu\u1ed1c\u00a0\u1ee9c ch\u1ebf men chuy\u1ec3n(ACEI)<\/strong>\/ thu\u1ed1c \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 Angiotensin (ARB) k\u1ebft h\u1ee3p v\u1edbi ch\u1eb9n k\u00eanh calcium. D\u1ea1ng thu\u1ed1c ph\u1ed1i h\u1ee3p ACEI\/ARB v\u1edbi\u00a0thu\u1ed1c l\u1ee3i ti\u1ec3u\u00a0c\u0169ng hay \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn do c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb t\u1ed1t. C\u00f3 kh\u00e1 nhi\u1ec1u thu\u1ed1c ph\u1ed1i h\u1ee3p m\u1ed9t ch\u1ea5t l\u1ee3i ti\u1ec3u k\u1ebft h\u1ee3p v\u1edbi ARB\/ACEI\/ch\u1eb9n k\u00eanh calcium. D\u1ea1ng thu\u1ed1c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t ch\u1eb9n beta k\u1ebft h\u1ee3p v\u1edbi ch\u1eb9n k\u00eanh calcium c\u00f3 t\u00e1c d\u1ee5ng gi\u00e3n m\u1ea1ch l\u00e0m h\u1ea1 huy\u1ebft \u00e1p v\u00e0 duy tr\u00ec li\u1ec1u \u0111i\u1ec1u tr\u1ecb kh\u00e1 d\u1ec5 d\u00e0ng.<\/p>\n

B\u1ec7nh nh\u00e2n THA l\u00e2u n\u0103m th\u01b0\u1eddng c\u00f3 k\u00e8m b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng ho\u1eb7c b\u1ec7nh th\u1eadn m\u1ea1n l\u00e0 nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng c\u00f3 th\u1ec3 c\u1ea7n d\u00f9ng ph\u00e1c \u0111\u1ed3 thu\u1ed1c ph\u1ed1i h\u1ee3p 3 ho\u1ea1t ch\u1ea5t tr\u1edf l\u00ean. Tuy nhi\u00ean hi\u1ec7n n\u00e0y c\u00f3 \u00edt s\u1ed1 li\u1ec7u \u0111\u00e1nh gi\u00e1 v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng 3 thu\u1ed1c huy\u1ebft \u00e1p tr\u1edf l\u00ean n\u00ean vi\u1ec7c d\u00f9ng thu\u1ed1c ch\u1ee7 y\u1ebfu d\u1ef1a tr\u00ean kinh nghi\u1ec7m c\u1ee7a th\u1ea7y thu\u1ed1c. Khi b\u1ec7nh nh\u00e2n d\u00f9ng m\u1ed9t thu\u1ed1c huy\u1ebft \u00e1p m\u00e0 kh\u00f4ng hi\u1ec7u qu\u1ea3, c\u00e1c th\u1ea7y thu\u1ed1c c\u00f3 th\u1ec3 ch\u1ecdn c\u00e1ch t\u0103ng d\u1ea7n li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a thu\u1ed1c \u0111ang d\u00f9ng ho\u1eb7c thay th\u1ebf thu\u1ed1c \u0111ang s\u1eed d\u1ee5ng b\u1eb1ng thu\u1ed1c kh\u00e1c. Vi\u1ec7c t\u0103ng li\u1ec1u hay thay thu\u1ed1c s\u1ebd ph\u1ee9c t\u1ea1p v\u00e0 c\u00f3 nguy c\u01a1 m\u1eafc c\u00e1c ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i c\u1ee7a thu\u1ed1c (ADR) nhi\u1ec1u h\u01a1n. V\u00ec v\u1eady n\u00ean l\u1ef1a ch\u1ecdn ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p 3 thu\u1ed1c d\u00f9ng trong 5 nh\u00f3m thu\u1ed1c sau: \u1ee8c ch\u1ebf men chuy\u1ec3n (ACEi), \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 Angiotensin(ARB), l\u1ee3i ti\u1ec3u thiazide, ch\u1eb9n k\u00eanh calcium v\u00e0 ch\u1eb9n beta giao c\u1ea3m.<\/p>\n

Trong c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00fd t\u0103ng huy\u1ebft \u00e1p (THA) hi\u1ec7n nay, vi\u1ec7c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t \u0111\u01b0\u1ee3c c\u00e1c th\u1ea7y thu\u1ed1c r\u1ea5t hay s\u1eed d\u1ee5ng. M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n khi d\u00f9ng \u0111\u01a1n l\u1ebb m\u1ed9t thu\u1ed1c huy\u1ebft \u00e1p th\u01b0\u1eddng kh\u00f3 duy tr\u00ec \u0111\u01b0\u1ee3c m\u1ee9c huy\u1ebft \u00e1p m\u1ee5c ti\u00eau. V\u00ec v\u1eady, \u00e1p d\u1ee5ng ph\u00e1c \u0111\u1ed3 ph\u1ed1i h\u1ee3p thu\u1ed1c trong \u0111i\u1ec1u tr\u1ecb THA \u0111\u00e3 tr\u1edf n\u00ean ng\u00e0y c\u00e0ng th\u00f4ng d\u1ee5ng nh\u1eb1m \u0111\u1ea1t \u0111\u01b0\u1ee3c tr\u1ecb s\u1ed1 huy\u1ebft \u00e1p mong mu\u1ed1n cho ng\u01b0\u1eddi b\u1ec7nh \u0111\u1ed3ng th\u1eddi gi\u00fap b\u1ea3o v\u1ec7 m\u1ea1ch m\u00e1u n\u00e3o, th\u1eadn v\u00e0 tim.<\/p>\n

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Sinh vi\u00ean Khoa D\u01b0\u1ee3c Tr\u01b0\u1eddng Cao \u0111\u1eb3ng Y H\u00e0 N\u1ed9i trong gi\u1edd th\u1ef1c h\u00e0nh t\u1ea1i ph\u00f2ng th\u00ed nghi\u1ec7m<\/figcaption><\/figure>\n

\u0110\u1ec3 gi\u00fap cho ng\u01b0\u1eddi b\u1ec7nh b\u1ecb THA kh\u00f4ng ph\u1ea3i d\u00f9ng \u0111\u1ed3ng th\u1eddi 2-3 ho\u1eb7c 4 thu\u1ed1c v\u1edbi c\u00e1c ho\u1ea1t ch\u1ea5t \u0111\u01a1n l\u1ebb c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p \u0111\u1ebfn m\u1ee9c c\u1ea7n duy tr\u00ec, c\u00e1c nh\u00e0 b\u00e0o ch\u1ebf d\u01b0\u1ee3c ph\u1ea9m \u0111\u00e3 \u0111\u01b0a ra th\u1ecb tr\u01b0\u1eddng kh\u00e1 nhi\u1ec1u d\u1ea1ng thu\u1ed1c m\u00e0 trong m\u1ed7i vi\u00ean thu\u1ed1c \u0111\u00e3 ph\u1ed1i h\u1ee3p nhi\u1ec1u ho\u1ea1t ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p, duy tr\u00ec m\u1ee9c huy\u1ebft \u00e1p an to\u00e0n cho ng\u01b0\u1eddi b\u1ec7nh. V\u00ec v\u1eady, hi\u1ec7n nay c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb THA v\u1edbi th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t ph\u1ed1i h\u1ee3p 2 ho\u1eb7c 3 ch\u1ea5t kh\u00e1c nhau l\u00e0 r\u1ea5t ph\u1ed5 bi\u1ebfn. Ng\u01b0\u1eddi d\u00f9ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb THA c\u1ea7n bi\u1ebft \u0111\u1eb7c t\u00ednh c\u1ee7a thu\u1ed1c m\u00ecnh \u0111ang s\u1eed d\u1ee5ng \u0111\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi th\u1ea7y thu\u1ed1c l\u1ef1a ch\u1ecdn d\u1ea1ng b\u00e0o ch\u1ebf ph\u00f9 h\u1ee3p v\u1edbi m\u1ed7i c\u00e1 th\u1ec3.<\/p>\n

Vi\u1ec7c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t trong m\u1ed9t vi\u00ean thu\u1ed1c mang l\u1ea1i hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p t\u1ed1t h\u01a1n v\u00e0 gi\u1ea3m nguy c\u01a1 b\u1ec7nh l\u00fd kh\u00e1c cao h\u01a1n so v\u1edbi vi\u1ec7c t\u0103ng li\u1ec1u d\u00f9ng c\u1ee7a m\u1ed9t thu\u1ed1c ch\u1ec9 c\u00f3 m\u1ed9t ho\u1ea1t ch\u1ea5t. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u cho th\u1ea5y vi\u1ec7c ph\u1ed1i h\u1ee3p 2 ho\u1ea1t ch\u1ea5t t\u01b0\u01a1ng h\u1ee3p hi\u1ec7p \u0111\u1ed3ng c\u1ed9ng trong m\u1ed9t thu\u1ed1c gi\u00fap l\u00e0m gi\u1ea3m huy\u1ebft \u00e1p nhi\u1ec1u h\u01a1n \u0111\u1ebfn 5 l\u1ea7n so v\u1edbi vi\u1ec7c t\u0103ng g\u1ea5p \u0111\u00f4i li\u1ec1u c\u1ee7a thu\u1ed1c ch\u1ec9 c\u00f3 m\u1ed9t ho\u1ea1t ch\u1ea5t. Ngo\u00e0i ra, l\u1ee3i \u00edch c\u1ee7a \u0111i\u1ec1u tr\u1ecb THA \u0111a ho\u1ea1t ch\u1ea5t gi\u00fap t\u0103ng hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p, gi\u1ea3m t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c, c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n \u0111\u1ed9 dung n\u1ea1p c\u1ee7a b\u1ec7nh nh\u00e2n, gi\u1ea3m bi\u1ebfn c\u1ed1 tim m\u1ea1ch v\u00e0 t\u1eed vong do bi\u1ebfn c\u1ed1 \u0111\u00f3.<\/p>\n

M\u1ed9t s\u1ed1 d\u1ea1ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb THA ph\u1ed1i h\u1ee3p ph\u1ed5 bi\u1ebfn hi\u1ec7n nay hay c\u00f3 tr\u00ean th\u1ecb tr\u01b0\u1eddng l\u00e0 thu\u1ed1c\u00a0\u1ee9c ch\u1ebf men chuy\u1ec3n(ACEI)<\/strong>\/ thu\u1ed1c \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 Angiotensin (ARB) k\u1ebft h\u1ee3p v\u1edbi ch\u1eb9n k\u00eanh calcium. D\u1ea1ng thu\u1ed1c ph\u1ed1i h\u1ee3p ACEI\/ARB v\u1edbi\u00a0thu\u1ed1c l\u1ee3i ti\u1ec3u\u00a0c\u0169ng hay \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn do c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb t\u1ed1t. C\u00f3 kh\u00e1 nhi\u1ec1u thu\u1ed1c ph\u1ed1i h\u1ee3p m\u1ed9t ch\u1ea5t l\u1ee3i ti\u1ec3u k\u1ebft h\u1ee3p v\u1edbi ARB\/ACEI\/ch\u1eb9n k\u00eanh calcium. D\u1ea1ng thu\u1ed1c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t ch\u1eb9n beta k\u1ebft h\u1ee3p v\u1edbi ch\u1eb9n k\u00eanh calcium c\u00f3 t\u00e1c d\u1ee5ng gi\u00e3n m\u1ea1ch l\u00e0m h\u1ea1 huy\u1ebft \u00e1p v\u00e0 duy tr\u00ec li\u1ec1u \u0111i\u1ec1u tr\u1ecb kh\u00e1 d\u1ec5 d\u00e0ng.<\/p>\n

B\u1ec7nh nh\u00e2n THA l\u00e2u n\u0103m th\u01b0\u1eddng c\u00f3 k\u00e8m b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng ho\u1eb7c b\u1ec7nh th\u1eadn m\u1ea1n l\u00e0 nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng c\u00f3 th\u1ec3 c\u1ea7n d\u00f9ng ph\u00e1c \u0111\u1ed3 thu\u1ed1c ph\u1ed1i h\u1ee3p 3 ho\u1ea1t ch\u1ea5t tr\u1edf l\u00ean. Tuy nhi\u00ean hi\u1ec7n n\u00e0y c\u00f3 \u00edt s\u1ed1 li\u1ec7u \u0111\u00e1nh gi\u00e1 v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng 3 thu\u1ed1c huy\u1ebft \u00e1p tr\u1edf l\u00ean n\u00ean vi\u1ec7c d\u00f9ng thu\u1ed1c ch\u1ee7 y\u1ebfu d\u1ef1a tr\u00ean kinh nghi\u1ec7m c\u1ee7a th\u1ea7y thu\u1ed1c. Khi b\u1ec7nh nh\u00e2n d\u00f9ng m\u1ed9t thu\u1ed1c huy\u1ebft \u00e1p m\u00e0 kh\u00f4ng hi\u1ec7u qu\u1ea3, c\u00e1c th\u1ea7y thu\u1ed1c c\u00f3 th\u1ec3 ch\u1ecdn c\u00e1ch t\u0103ng d\u1ea7n li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a thu\u1ed1c \u0111ang d\u00f9ng ho\u1eb7c thay th\u1ebf thu\u1ed1c \u0111ang s\u1eed d\u1ee5ng b\u1eb1ng thu\u1ed1c kh\u00e1c. Vi\u1ec7c t\u0103ng li\u1ec1u hay thay thu\u1ed1c s\u1ebd ph\u1ee9c t\u1ea1p v\u00e0 c\u00f3 nguy c\u01a1 m\u1eafc c\u00e1c ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i c\u1ee7a thu\u1ed1c (ADR) nhi\u1ec1u h\u01a1n. V\u00ec v\u1eady n\u00ean l\u1ef1a ch\u1ecdn ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p 3 thu\u1ed1c d\u00f9ng trong 5 nh\u00f3m thu\u1ed1c sau: \u1ee8c ch\u1ebf men chuy\u1ec3n (ACEi), \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 Angiotensin(ARB), l\u1ee3i ti\u1ec3u thiazide, ch\u1eb9n k\u00eanh calcium v\u00e0 ch\u1eb9n beta giao c\u1ea3m.<\/p>\n

Ph\u1ed1i h\u1ee3p\u00a0thu\u1ed1c \u0111i\u1ec1u tr\u1ecb THA\u00a0v\u1edbi 4 thu\u1ed1c c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong tr\u01b0\u1eddng h\u1ee3p n\u1ebfu 3 thu\u1ed1c huy\u1ebft \u00e1p \u0111\u00e3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u t\u0103ng d\u1ea7n c\u00e1c thu\u1ed1c v\u00e0 thay th\u1ebf thu\u1ed1c nh\u01b0ng kh\u00f4ng hi\u1ec7u qu\u1ea3 v\u00e0 b\u1ec7nh nh\u00e2n \u0111\u00e3 t\u1ea7m so\u00e1t k\u1ef9 c\u00e1c nguy\u00ean nh\u00e2n c\u00f3 th\u1ec3 g\u00e2y ra THA. M\u1ed9t s\u1ed1 thu\u1ed1c l\u1ee3i ti\u1ec3u kh\u00e1ng aldosterone\u00a0 nh\u01b0 spironolactone hay eplerenone s\u1ebd \u0111\u01b0\u1ee3c l\u1ee5a ch\u1ecdn \u0111\u01b0a v\u00e0o ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb. \u0110ang d\u00f9ng l\u1ee3i ti\u1ec3u v\u1edbi ACEIs\/ARB v\u00e0 ch\u1eb9n beta th\u00ec b\u1ed5 sung ch\u1eb9n k\u00eanh calcium; n\u1ebfu \u0111ang d\u00f9ng l\u1ee3i ti\u1ec3u + ch\u1eb9n k\u00eanh calcium v\u00e0 thu\u1ed1c ACEIs\/ARB th\u00ec th\u00eam ch\u1eb9n beta.Trong tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng th\u1ec3 th\u00eam \u0111\u01b0\u1ee3c c\u00e1c thu\u1ed1c l\u1ef1a ch\u1ecdn h\u00e0ng \u0111\u1ea7u m\u1edbi ti\u1ebfp \u0111\u1ebfn th\u00eam c\u00e1c thu\u1ed1c h\u00e0ng 2 nh\u01b0\u00a0ch\u1eb9n alpha, gi\u00e3n m\u1ea1ch tr\u1ef1c ti\u1ebfp…Ph\u1ed1i h\u1ee3p l\u1ee3i ti\u1ec3u v\u1edbi thu\u1ed1c ch\u1eb9n beta n\u00ean tr\u00e1nh \u1edf c\u00e1c b\u1ec7nh nh\u00e2n c\u00f3 h\u1ed9i ch\u1ee9ng chuy\u1ec3n h\u00f3a v\u00e0 b\u1ec7nh nh\u00e2n nguy c\u01a1 ti\u1ec3u \u0111\u01b0\u1eddng cao, tr\u1eeb khi \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh c\u00f3 l\u00fd do \u0111\u1eb7c bi\u1ec7t. B\u1edfi v\u00ec \u0111i\u1ec1u n\u00e0y l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng.<\/p>\n

Vi\u1ec7c d\u00f9ng nhi\u1ec1u thu\u1ed1c v\u1edbi nhau c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 h\u1ea1 \u00e1p t\u01b0 th\u1ebf. Ng\u01b0\u1eddi b\u1ec7nh b\u1ecb THA \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c thu\u1ed1c ph\u1ed1i h\u1ee3p c\u1ea7n thay \u0111\u1ed5i t\u01b0 th\u1ebf m\u1ed9t c\u00e1ch ch\u1eadm v\u00e0 c\u1ea7n t\u1eadp th\u00f3i quen n\u00e0y. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh l\u1ed1i s\u1ed1ng v\u00e0 ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, duy tr\u00ec c\u00e2n n\u1eb7ng h\u1ee3p l\u00fd \u0111\u1ec3 gi\u00fap ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p t\u1ed1t h\u01a1n. Nh\u00f3m thu\u1ed1c \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd tim m\u1ea1ch nh\u01b0 THA c\u00f3 kh\u00e1 nhi\u1ec1u ADR kh\u00f4ng mong mu\u1ed1n. Tr\u00ean th\u1ecb tr\u01b0\u1eddng thu\u1ed1c hi\u1ec7n nay, c\u00e1c nh\u00e0 thu\u1ed1c \u0111ang gi\u1edbi thi\u1ec7u qu\u1ea3ng c\u00e1o v\u00e0 b\u00e1n kh\u00e1 nhi\u1ec1u thu\u1ed1c ph\u1ed1i h\u1ee3p tr\u00ean m\u1ed9t ho\u1ea1t ch\u1ea5t v\u1edbi nhi\u1ec1u t\u00ean bi\u1ec7t d\u01b0\u1ee3c c\u1ee7a c\u00e1c h\u00e3ng d\u01b0\u1ee3c ph\u1ea9m n\u1ed5i ti\u1ebfng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb THA. Ng\u01b0\u1eddi b\u1ec7nh THA c\u1ea7n \u0111i kh\u00e1m b\u1ec7nh, tu\u00e2n th\u1ee7 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a th\u1ea7y thu\u1ed1c \u0111\u1ec3 l\u1ef1a ch\u1ecdn d\u1ea1ng thu\u1ed1c ph\u00f9 h\u1ee3p v\u1edbi c\u01a1 \u0111\u1ecba c\u1ee7a m\u00ecnh, tr\u00e1nh c\u00e1c ADR hay g\u1eb7p khi d\u00f9ng thu\u1ed1c th\u01b0\u1eddng xuy\u00ean d\u00e0i ng\u00e0y v\u00e0 tr\u00e1nh nguy c\u01a1 ph\u1ed1i h\u1ee3p qu\u00e1 nhi\u1ec1u d\u1ec5 b\u1ecb h\u1ea1 huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c c\u1ea7n ph\u1ea3i duy tr\u00ec.\/.<\/p>\n

ThS L\u00ea Qu\u1ed1c Th\u1ecbnh- Gi\u1ea3ng vi\u00ean Khoa D\u01b0\u1ee3c<\/strong><\/p>\n

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 <\/p>\n","protected":false},"excerpt":{"rendered":"

Trong c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00fd t\u0103ng huy\u1ebft \u00e1p (THA) hi\u1ec7n nay, vi\u1ec7c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t \u0111\u01b0\u1ee3c c\u00e1c th\u1ea7y thu\u1ed1c r\u1ea5t hay s\u1eed d\u1ee5ng. M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n khi d\u00f9ng \u0111\u01a1n l\u1ebb m\u1ed9t thu\u1ed1c huy\u1ebft \u00e1p th\u01b0\u1eddng kh\u00f3 duy tr\u00ec \u0111\u01b0\u1ee3c m\u1ee9c huy\u1ebft \u00e1p m\u1ee5c ti\u00eau. V\u00ec v\u1eady, \u00e1p d\u1ee5ng ph\u00e1c \u0111\u1ed3 […]\n","protected":false},"author":20,"featured_media":5645,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,1719,2398,1],"tags":[6057,6056,6058],"yoast_head":"\nNh\u1eefng thu\u1ed1c m\u1edbi k\u1ebft h\u1ee3p ho\u1ea1t ch\u1ea5t trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p - Tr\u01b0\u1eddng Cao \u0110\u1eb3ng Y H\u00e0 N\u1ed9i<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/jhasim1.com\/nhung-thuoc-moi-ket-hop-hoat-chat-trong-dieu-tri-tang-huyet-ap.html\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nh\u1eefng thu\u1ed1c m\u1edbi k\u1ebft h\u1ee3p ho\u1ea1t ch\u1ea5t trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p\" \/>\n<meta property=\"og:description\" content=\"Trong c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00fd t\u0103ng huy\u1ebft \u00e1p (THA) hi\u1ec7n nay, vi\u1ec7c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t \u0111\u01b0\u1ee3c c\u00e1c th\u1ea7y thu\u1ed1c r\u1ea5t hay s\u1eed d\u1ee5ng. 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