{"id":6349,"date":"2024-05-02T17:03:39","date_gmt":"2024-05-02T10:03:39","guid":{"rendered":"https:\/\/jhasim1.com\/?p=6349"},"modified":"2024-05-03T07:45:56","modified_gmt":"2024-05-03T00:45:56","slug":"mot-so-loai-thuoc-dieu-tri-benh-tieu-duong-the-he-moi","status":"publish","type":"post","link":"https:\/\/jhasim1.com\/mot-so-loai-thuoc-dieu-tri-benh-tieu-duong-the-he-moi.html","title":{"rendered":"M\u1ed9t s\u1ed1 loa\u0323i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng th\u1ebf h\u1ec7 m\u1edbi"},"content":{"rendered":"

B\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng (hay c\u00f2n g\u1ecdi l\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng) c\u00f3 xu h\u01b0\u1edbng ng\u00e0y c\u00e0ng gia t\u0103ng, do l\u1ed1i s\u1ed1ng v\u00e0 \u0103n u\u1ed1ng. Hi\u1ec7n nay, Vi\u1ec7t Nam c\u00f3 kho\u1ea3ng 7 tri\u1ec7u ng\u01b0\u1eddi m\u1eafc \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, v\u1edbi h\u01a1n 55% b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 bi\u1ebfn ch\u1ee9ng, trong \u0111\u00f3 34% l\u00e0 bi\u1ebfn ch\u1ee9ng v\u1ec1 tim m\u1ea1ch; 39,5% bi\u1ebfn ch\u1ee9ng v\u1ec1 m\u1eaft v\u00e0 bi\u1ebfn ch\u1ee9ng v\u1ec1 th\u1ea7n kinh; 24% bi\u1ebfn ch\u1ee9ng v\u1ec1 th\u1eadn. V\u1edbi s\u1ef1 ti\u1ebfn b\u1ed9 v\u01b0\u1ee3t b\u1eadc c\u1ee7a c\u00f4ng ngh\u1ec7 b\u00e0o ch\u1ebf d\u01b0\u1ee3c ph\u1ea9m, h\u00e0ng lo\u1ea1t thu\u1ed1c tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng th\u1ebf h\u1ec7 m\u1edbi \u0111\u00e3 ra \u0111\u1eddi, k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c c\u0169, ph\u1ed5 bi\u1ebfn nh\u1ea5t l\u00e0 d\u1ea1ng u\u1ed1ng Metformin \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh c\u00f3 hi\u1ec7u qu\u1ea3 t\u1ed1t.<\/p>\n

Metformin l\u00e0 m\u1ed9t loa\u0323i thu\u1ed1c tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng thu\u1ed9c nh\u00f3m thu\u00f4\u0301c Biguanid, l\u00e0m gi\u1ea3m s\u1ea3n xu\u1ea5t glucose trong gan, tr\u00ec ho\u00e3n s\u1ef1 h\u1ea5p th\u1ee5 \u0111\u01b0\u1eddng t\u1ea1i ru\u1ed9t v\u00e0 t\u0103ng \u0111\u1ed9 nh\u1ea1y c\u1ea3m c\u1ee7a c\u01a1 th\u1ec3 v\u1edbi Insulin. N\u00f3 \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o nhi\u1ec1u ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb v\u00e0 kh\u00e1 quen thu\u1ed9c v\u1edbi b\u1ec7nh nh\u00e2n. Tuy nhi\u00ean, b\u00ean c\u1ea1nh d\u00f9ng thu\u1ed1c, c\u1ea7n c\u00f3 ch\u1ebf \u0111\u1ed9 t\u1eadp luy\u1ec7n v\u1eeba s\u1ee9c, gi\u1ea3m c\u00e2n, \u0103n u\u1ed1ng \u0111i\u1ec1u \u0111\u1ed9 v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00e1c bi\u1ebfn ch\u1ee9ng c\u1ee7a b\u1ec7nh, bao g\u1ed3m \u0111i\u1ec1u tr\u1ecb b\u1ec7nh t\u0103ng huy\u1ebft \u00e1p, gi\u1ea3m thi\u1ec3u bi\u1ebfn c\u1ed1 tim m\u1ea1ch ho\u1eb7c t\u1eed vong do b\u1ec7nh tim m\u1ea1ch v\u00e0 gi\u1ea3m ti\u1ebfn tri\u1ec3n bi\u1ebfn ch\u1ee9ng tr\u00ean th\u1eadn do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/p>\n

\"\"
Sinh ho\u1ea1t nh\u00f3m c\u1ed9ng \u0111\u1ed3ng d\u00f9ng thu\u1ed1c trong B\u1ec7nh vi\u00ean : Th\u1ea7y thu\u1ed1c h\u01b0\u1edbng d\u1eabn b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng c\u00e1ch s\u1eed d\u1ee5ng thu\u1ed1c<\/em><\/figcaption><\/figure>\n

C\u00e1c thu\u1ed1c tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng th\u1ebf h\u1ec7 m\u1edbi c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m c\u00e2n, n\u00ean thi\u0301ch h\u01a1\u0323p cho nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng k\u00e8m t\u00ecnh tr\u1ea1ng th\u1eeba c\u00e2n, b\u00e9o ph\u00ec.<\/p>\n

Empagliflozin l\u00e0 thu\u1ed1c m\u1edbi thu\u1ed9c nh\u00f3m \u1ee9c ch\u1ebf k\u00eanh \u0111\u1ed3ng v\u1eadn chuy\u1ec3n SGLT2, l\u00e0m t\u0103ng th\u1ea3i glucose qua \u0111\u01b0\u1eddng ti\u1ec3u t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m l\u01b0\u01a1\u0323ng \u0111\u01b0\u1eddng trong m\u00e1u. \u01afu \u0111i\u1ec3m \u0111\u1eb7c bi\u1ec7t c\u1ee7a nh\u00f3m thu\u1ed1c \u01b0\u0301c ch\u00ea\u0301 SGLT2 bao g\u1ed3m mang la\u0323i l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i \u0111\u00f4\u0301i v\u01a1\u0301i tim m\u1ea1ch \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng, cho th\u00e2\u0301y nh\u01b0\u0303ng b\u01b0\u1edbc ti\u00ea\u0301n hi\u1ec7u qu\u1ea3 trong vi\u00ea\u0323c b\u1ea3o v\u1ec7 th\u1eadn. \u0110\u00e2y l\u00e0 thu\u1ed1c u\u1ed1ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng thay th\u1ebf cho nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ2 kh\u00f4ng th\u1ec3 s\u1eed d\u1ee5ng thu\u00f4\u0301c Metformin. Ngo\u00e0i ra, n\u00f3 c\u0169ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb suy tim, v\u00ec hi\u1ec7u qu\u1ea3 l\u00e0m gi\u1ea3m bi\u1ebfn c\u1ed1 tim m\u1ea1ch \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh qua c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng. Th\u1ebf n\u00ean, \u0111\u00e2y l\u00e0 l\u1ef1a ch\u1ecdn h\u00e0ng \u0111\u1ea7u cho b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng c\u00f3 k\u00e8m b\u1ec7nh tim m\u1ea1ch.<\/p>\n

Dapagliflozin c\u0169ng thu\u1ed9c nh\u00f3m \u1ee9c ch\u1ebf protein SGLT2 gi\u00fap lo\u1ea1i b\u1ecf m\u1ed9t l\u01b0\u1ee3ng l\u1edbn glucose trong m\u00e1u qua th\u1eadn v\u00e0 b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u, t\u1eeb \u0111\u00f3 gi\u00fap h\u1ea1 \u0111\u01b0\u1eddng huy\u00ea\u0301t trong m\u00e1u. N\u00f3 c\u0169ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb b\u1ec7nh th\u1eadn m\u1ea1n \u1edf ng\u01b0\u1eddi l\u1edbn.<\/p>\n

\u0110\u00e1ng ch\u00fa \u00fd,\u00a0m\u1ed9t s\u1ed1 thu\u1ed1c th\u1ebf h\u1ec7 m\u1edbi hi\u1ec7n nay c\u00f3 tr\u00ean th\u1ecb tr\u01b0\u1eddng l\u00e0 s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a\u00a02 lo\u1ea1i thu\u1ed1c tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng l\u00e0 Metformin v\u00e0 Linagliptin. Linagliptin l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf DPP-4, c\u00f3 t\u00e1c d\u1ee5ng t\u0103ng gi\u1ea3i ph\u00f3ng Insulin t\u1eeb tuy\u1ebfn t\u1ee5y v\u00e0 gi\u1ea3m c\u00e1c hormon l\u00e0m t\u0103ng l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u, gi\u00fap gi\u1ea3m c\u1ea3 l\u01b0\u1ee3ng \u0111\u01b0\u1eddng l\u00fac \u0111\u00f3i v\u00e0 sau b\u1eefa \u0103n. S\u1ef1 ph\u1ed1i h\u1ee3p 2 thu\u1ed1c n\u00e0y gi\u00fap ki\u1ec3m so\u00e1t l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u t\u1ed1t h\u01a1n, gi\u00fap ng\u0103n ng\u1eeba c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng nh\u01b0 t\u1ed5n th\u01b0\u01a1ng th\u1eadn, m\u00f9 l\u00f2a v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nguy c\u01a1 b\u1ecb \u0111au tim ho\u1eb7c \u0111\u1ed9t qu\u1ef5.<\/p>\n

\"Gi\u1edbi
D\u00f9ng thu\u1ed1c tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng \u0111\u00fang c\u00e1ch \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft m\u1ee5c ti\u00eau trong gi\u1edbi h\u1ea1n an to\u00e0n<\/em><\/figcaption><\/figure>\n

Hi\u1ec7n nay c\u00f3 kh\u00e1 nhi\u1ec1u d\u1ea1ng b\u00fat ti\u00eam Insulin th\u1ebf h\u1ec7 m\u1edbi v\u1edbi th\u00e0nh ph\u1ea7n l\u00e0 Insulin lispro- m\u1ed9t lo\u1ea1i Insulin t\u00e1c d\u1ee5ng nhanh \u1edf ng\u01b0\u1eddi m\u0103\u0301c b\u00ea\u0323nh ti\u00ea\u0309u \u0111\u01b0\u01a1\u0300ng \u0111\u1ec3 c\u1ea3i thi\u1ec7n vi\u1ec7c ki\u1ec3m so\u00e1t l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u. B\u00fat ti\u00eam Insulin \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u1edbn m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng t\u00fdp 2 ho\u1eb7c m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng t\u00fdp 1. Tuy theo t\u1eebng th\u1ef1c th\u1ec3 v\u00e0 t\u00ecnh tr\u1ea1ng \u0111\u01b0\u1eddng huy\u1ebft \u0111\u1ec3 ch\u1ecdn b\u00fat \u0111\u00fang li\u1ec1u l\u01b0\u1ee3ng v\u00e0 \u0111\u1ed1i t\u01b0\u1ee3ng thu\u1ed1c b\u00fat ti\u00eam c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Lispro Insulin an to\u00e0n, hi\u1ec7u qu\u1ea3 m\u00e0 l\u1ea1i c\u00f3 gi\u00e1 th\u00e0nh th\u1ea5p h\u01a1n nhi\u1ec1u so v\u1edbi m\u1ed9t s\u1ed1 d\u1ea1ng b\u00fat ti\u00eam Insulin tr\u01b0\u1edbc \u0111\u00e2y. Do \u0111\u00f3, \u0111\u00e2y l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn thay th\u1ebf gi\u00fap ti\u1ebft ki\u1ec7m chi ph\u00ed cho b\u1ec7nh nh\u00e2n m\u1eafc ti\u1ec3u \u0111\u01b0\u1eddng.<\/p>\n

B\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng\u00a0l\u00e0 b\u1ec7nh chuy\u1ec3n h\u00f3a, kh\u00f4ng l\u00e2y nhi\u1ec5m v\u00e0 hi\u1ec7n nay \u0111ang c\u00f3 xu h\u01b0\u1edbng ng\u00e0y c\u00e0ng tr\u1ebb h\u00f3a. Th\u1eadm ch\u00ed, \u0111\u00e3 c\u00f3 nhi\u1ec1u tr\u1ebb em b\u00e9o ph\u00ec m\u1eafc \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng. Nhi\u1ec1u ng\u01b0\u1eddi c\u00f3 th\u00f3i quen l\u1ed1i s\u1ed1ng ch\u01b0a l\u00e0nh m\u1ea1nh nh\u01b0 b\u1ecf b\u1eefa s\u00e1ng, \u0103n qu\u00e1 nhi\u1ec1u ch\u1ea5t b\u00e9o v\u00e0 th\u1ef1c ph\u1ea9m gi\u00e0u n\u0103ng l\u01b0\u1ee3ng, \u0111\u01b0\u1eddng tinh b\u1ed9t d\u1eabn \u0111\u1ebfn m\u1eafc b\u1ec7nh n\u00e0y. Nh\u1eefng ng\u01b0\u1eddi c\u00f3 l\u1ed1i s\u1ed1ng \u00edt v\u1eadn \u0111\u1ed9ng, th\u1eeba c\u00e2n, b\u00e9o ph\u00ec g\u00e2y d\u01b0 th\u1eeba l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u l\u00e2u ng\u00e0y c\u0169ng d\u1eabn \u0111\u1ebfn m\u1eafc ti\u1ec3u \u0111\u01b0\u1eddng. B\u00ean c\u1ea1nh ch\u1ebf \u0111\u1ed9 d\u00f9ng thu\u1ed1c theo h\u01b0\u1edbng d\u1eabn, ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n tu\u00e2n th\u1ee7 ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng nh\u01b0 h\u1ea1n ch\u1ebf \u0111\u01b0\u1eddng tinh b\u1ed9t, th\u1ef1c ph\u1ea9m \u0111\u01b0\u1eddng huy\u1ebft cao; \u01b0u ti\u00ean th\u1ef1c ph\u1ea9m gi\u00e0u ch\u1ea5t x\u01a1 nh\u01b0 rau qu\u1ea3 t\u01b0\u01a1i.<\/p>\n

Ngo\u00e0i ra, c\u1ea7n\u00a0t\u1eadp th\u1ec3 d\u1ee5c \u0111\u1ec1u \u0111\u1eb7n \u00edt nh\u1ea5t 30 ph\u00fat\/ng\u00e0y \u0111\u1ec3 l\u00e0m ch\u1eadm bi\u1ebfn ch\u1ee9ng. Ng\u01b0\u1eddi b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng\u00a0c\u0169ng ph\u1ea3i th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra \u0111\u01b0\u1eddng huy\u1ebft b\u1eb1ng m\u00e1y t\u1ef1 \u0111o \u1edf nh\u00e0 ho\u1eb7c ra c\u00e1c nh\u00e0 thu\u1ed1c ki\u1ec3m tra mi\u1ec5n ph\u00ed. Y t\u1ebf c\u01a1 s\u1edf c\u1ea7n qu\u1ea3n l\u00fd c\u1ed9ng \u0111\u1ed3ng b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng\u00a0t\u1ea1i \u0111\u1ecba b\u00e0n d\u00e2n c\u01b0 v\u00e0 c\u00f3 nh\u1eefng ch\u01b0\u01a1ng tr\u00ecnh h\u1ed7 tr\u1ee3 \u0111\u1ec3 h\u1ecd d\u00f9ng thu\u1ed1c \u0111\u00fang c\u00e1ch v\u00e0 s\u1ed1ng t\u00edch c\u1ef1c theo h\u01b0\u1edbng ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft m\u1ee5c ti\u00eau b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng h\u1ee3p l\u00fd v\u00e0 t\u1eadp luy\u1ec7n v\u1eeba s\u1ee9c.<\/p>\n

ThS.L\u00ea Qu\u1ed1c Th\u1ecbnh – Gi\u1ea3ng vi\u00ean Khoa D\u01b0\u1ee3c<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

B\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng (hay c\u00f2n g\u1ecdi l\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng) c\u00f3 xu h\u01b0\u1edbng ng\u00e0y c\u00e0ng gia t\u0103ng, do l\u1ed1i s\u1ed1ng v\u00e0 \u0103n u\u1ed1ng. Hi\u1ec7n nay, Vi\u1ec7t Nam c\u00f3 kho\u1ea3ng 7 tri\u1ec7u ng\u01b0\u1eddi m\u1eafc \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, v\u1edbi h\u01a1n 55% b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 bi\u1ebfn ch\u1ee9ng, trong \u0111\u00f3 34% l\u00e0 bi\u1ebfn ch\u1ee9ng v\u1ec1 tim m\u1ea1ch; 39,5% […]\n","protected":false},"author":20,"featured_media":6353,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,1719,2398,1,1950],"tags":[],"class_list":["post-6349","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cao-dang-duoc","category-dao-tao","category-kien-thuc-y-duoc","category-tin-tuc","category-tin-y-te"],"yoast_head":"\nM\u1ed9t s\u1ed1 loa\u0323i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng th\u1ebf h\u1ec7 m\u1edbi - Tr\u01b0\u1eddng Cao \u0110\u1eb3ng Y H\u00e0 N\u1ed9i<\/title>\n<meta name=\"description\" content=\"B\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng (hay c\u00f2n g\u1ecdi l\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng) c\u00f3 xu h\u01b0\u1edbng ng\u00e0y c\u00e0ng gia t\u0103ng, do l\u1ed1i s\u1ed1ng v\u00e0 \u0103n u\u1ed1ng. 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