{"id":7044,"date":"2024-06-02T21:26:15","date_gmt":"2024-06-02T14:26:15","guid":{"rendered":"https:\/\/jhasim1.com\/?p=7044"},"modified":"2024-06-02T21:26:24","modified_gmt":"2024-06-02T14:26:24","slug":"thuoc-amoxicillin-clavulanate-san-pham-hay-gap-khi-sv-nhan-dien-thuoc-trong-thuc-hanh","status":"publish","type":"post","link":"https:\/\/jhasim1.com\/thuoc-amoxicillin-clavulanate-san-pham-hay-gap-khi-sv-nhan-dien-thuoc-trong-thuc-hanh.html","title":{"rendered":"Thu\u1ed1c Amoxicillin + Clavulanate: S\u1ea3n ph\u1ea9m hay g\u1eb7p khi SV nh\u1eadn di\u1ec7n thu\u1ed1c trong th\u1ef1c h\u00e0nh"},"content":{"rendered":"

Khi h\u1ecdc th\u1ef1c h\u00e0nh b\u00e1n thu\u1ed1c, Sinh vi\u00ean Khoa D\u01b0\u1ee3c r\u1ea5t hay g\u1eb7p lo\u1ea1i thu\u1ed1c Kh\u00e1ng sinh n\u00e0y trong nhi\u1ec1u t\u00ecnh hu\u1ed1ng d\u00f9ng thu\u1ed1c, k\u1ec3 c\u1ea3 c\u00e1c B\u1ec7nh \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, B\u1ec7nh \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, b\u1ec7nh \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u. C\u00e1c s\u1ea3n ph\u1ea9m th\u01b0\u01a1ng m\u1ea1i c\u1ee7a thu\u1ed1c Kh\u00e1ng sinh n\u00e0y c\u0169ng c\u00f3 r\u1ea5t nhi\u1ec1u t\u00ean kh\u00e1c nhau, nh\u01b0ng c\u00f4ng th\u1ee9c ph\u1ed1i h\u1ee3p ho\u1ea1t ch\u1ea5t th\u00ec l\u00e0 m\u1ed9t.C\u00e1c thu\u1ed1c lo\u1ea1i kh\u00e1ng sinh k\u1ebft h\u1ee3p \u0111\u1ed3ng th\u1eddi ch\u1ee9a Amoxicillin v\u00e0 Acid Clavulanic c\u00f3 t\u00e1c d\u1ee5ng t\u1ed1t h\u01a1n so v\u1edbi d\u00f9ng Amoxicillin \u0111\u1ed9c l\u1eadp. C\u00e1c tr\u01b0\u1eddng h\u1ee3p vi\u00eam m\u0169i h\u1ecdng n\u1eb7ng, k\u00e9o d\u00e0i v\u00e0 c\u00f3 nguy c\u01a1 bi\u1ebfn ch\u1ee9ng cao, b\u00e1c s\u0129 s\u1ebd \u01b0u ti\u00ean ch\u1ec9 \u0111\u1ecbnh Augmentin h\u01a1n l\u00e0 Amoxicillin.<\/strong><\/p>\n

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Amoxicillin l\u00e0 lo\u1ea1i kh\u00e1ng sinh thu\u1ed9c nh\u00f3m beta-lactam, c\u00f9ng h\u1ecd v\u1edbi Penicillin, hi\u1ec7n r\u1ea5t th\u00f4ng d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb vi\u00eam m\u0169i h\u1ecdng hay c\u00e1c b\u1ec7nh nhi\u1ec5m khu\u1ea9n kh\u00e1c. Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng t\u1ed1t v\u00e0 c\u0169ng c\u00f3 m\u00f9i v\u1ecb d\u1ec5 u\u1ed1ng, d\u1ec5 h\u1ea5p thu v\u00e0 \u00edt c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5. Ch\u00ednh v\u00ec th\u1ebf, thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng kh\u00e1 ph\u1ed5 bi\u1ebfn, nhi\u1ec1u khi \u0111\u00e3 b\u1ecb l\u1ea1m d\u1ee5ng\u00a0ho\u1eb7c\u00a0d\u00f9ng kh\u00f4ng \u0111\u1ee7 li\u1ec1u quy \u0111\u1ecbnh, n\u00ean ph\u1ed5 kh\u00e1ng khu\u1ea9n b\u1ecb h\u1ea1n ch\u1ebf v\u00e0 vi khu\u1ea9n c\u00f3 xu h\u01b0\u1edbng \u0111\u1ec1 kh\u00e1ng v\u1edbi Amoxicillin ng\u00e0y c\u00e0ng cao.<\/p>\n

Hi\u1ec7n nay, vi\u1ec7c d\u00f9ng m\u1ed9t lo\u1ea1i thu\u1ed1c k\u1ebft h\u1ee3p 2 ch\u1ea5t bao g\u1ed3m kh\u00e1ng sinh Amoxicillin v\u1edbi m\u1ed9t ch\u1ea5t kh\u00e1ng beta-lactamase \u0111\u1ec3 n\u00e2ng cao t\u00e1c d\u1ee5ng v\u00e0 ch\u1ed1ng \u0111\u1ec1 kh\u00e1ng thu\u1ed1c r\u1ea5t hay \u0111\u01b0\u1ee3c c\u00e1c th\u1ea7y thu\u1ed1c ch\u1ecdn l\u1ef1a \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n h\u01a1n l\u00e0 d\u00f9ng \u0111\u01a1n \u0111\u1ed9c m\u1ed9t m\u00ecnh Amoxicillin.<\/p>\n

M\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m th\u01b0\u01a1ng m\u1ea1i \u0111\u1ea7u ti\u00ean c\u1ee7a d\u1ea1ng ph\u1ed1i h\u1ee3p n\u00e0y hi\u1ec7n nay \u0111\u00e3 h\u1ebft quy\u1ec1n b\u1ea3o h\u1ed9 bi\u1ec7t d\u01b0\u1ee3c, n\u00ean tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 r\u1ea5t nhi\u1ec1u thu\u1ed1c generic v\u1edbi c\u00f4ng th\u1ee9c t\u01b0\u01a1ng t\u1ef1 v\u00e0 gi\u00e1 th\u00e0nh th\u1ea5p h\u01a1n,\u00a0n\u00ean c\u00e1c\u00a0th\u1ea7y thu\u1ed1c c\u00f3 nhi\u1ec1u s\u1ef1 l\u1ef1a ch\u1ecdn s\u1ea3n ph\u1ea9m ph\u00f9 h\u1ee3p v\u1edbi kinh t\u1ebf c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n

\"\"Ng\u01b0\u1eddi d\u00f9ng thu\u1ed1c c\u1ea7n l\u01b0u \u00fd c\u00e1ch \u0111\u1eb7t t\u00ean v\u00e0 ghi h\u00e0m l\u01b0\u1ee3ng c\u00f3 th\u1ec3 r\u1ea5t kh\u00e1c nhau nh\u01b0 s\u1ea3n ph\u1ea9m Bilclamos Bid 1000mg ch\u1ee9a 875mg Amoxicillin v\u00e0 125mg Acid Clavulanic; ho\u1eb7c nh\u01b0 thu\u1ed1c Klamentin 875\/125 c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Amoxicillin (d\u01b0\u1edbi d\u1ea1ng Amoxicilin Trihydrat) 875mg v\u00e0 Acid Clavulanic (d\u01b0\u1edbi d\u1ea1ng kali Clavulanat) 125mg. Th\u1ef1c t\u1ebf t\u1ea1i c\u00e1c hi\u1ec7u thu\u1ed1c, d\u1ea1ng b\u00e0o ch\u1ebf ph\u1ed1i h\u1ee3p 2 ch\u1ea5t theo c\u00f4ng th\u1ee9c n\u00e0y c\u00f2n c\u00f3 kh\u00e1 nhi\u1ec1u t\u00ean th\u01b0\u01a1ng m\u1ea1i kh\u00e1c n\u1eefa, nh\u01b0ng c\u00f4ng d\u1ee5ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng \u0111\u1ec1u nh\u01b0 nhau.Ngo\u00e0i ra c\u00f2n c\u00f3 c\u00e1c d\u1ea1ng ph\u1ed1i h\u1ee3p nh\u01b0 c\u00f4ng th\u1ee9c tr\u00ean nh\u1eefng v\u1edbi h\u00e0m l\u01b0\u1ee3ng nh\u1ecf h\u01a1n.<\/p>\n

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Augmentin l\u00e0 s\u1ea3n ph\u1ea9m \u0111\u1ea7u ti\u00ean c\u1ee7a GSK c\u00f3 th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t l\u00e0 k\u1ebft h\u1ee3p c\u1ee7a Amoxicillin v\u00e0 Clavulanate, l\u00e0 thu\u1ed1c kh\u00e1ng sinh ph\u1ed5 r\u1ed9ng thu\u1ed9c nh\u00f3m Penicillin. Amoxicillin (d\u01b0\u1edbi d\u1ea1ng Amoxicillin Trihydrate) c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng l\u1ea1i vi khu\u1ea9n g\u00e2y b\u1ec7nh, c\u00f2n Clavulanate (d\u01b0\u1edbi d\u1ea1ng Clavulanate Kali) \u0111\u00f3ng vai tr\u00f2 l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf beta-lactamase, gi\u00fap ch\u1ed1ng l\u1ea1i c\u00e1c ch\u1ee7ng vi khu\u1ea9n c\u00f3 kh\u1ea3 n\u0103ng \u0111\u1ec1 kh\u00e1ng nh\u00f3m Penicillin.<\/p>\n

Thu\u1ed1c Augmentin \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong tr\u01b0\u1eddng h\u1ee3p c\u1ea7n \u0111i\u1ec1u tr\u1ecb ng\u1eafn h\u1ea1n c\u00e1c lo\u1ea1i nhi\u1ec5m khu\u1ea9n g\u00e2y ra, b\u1edfi ch\u1ee7ng vi khu\u1ea9n nh\u1ea1y c\u1ea3m v\u1edbi t\u00e1c d\u1ee5ng c\u1ee7a Amoxicillin\/Clavulanate \u0111\u1ed1i v\u1edbi c\u00e1c v\u1ecb tr\u00ed nh\u01b0 \u1edf \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean (tai- m\u0169i- h\u1ecdng) nh\u01b0 vi\u00eam amidan t\u00e1i ph\u00e1t, vi\u00eam xoang, vi\u00eam tai gi\u1eefa. \u0110\u1ed1i v\u1edbi nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi, bao g\u1ed3m \u0111\u1ee3t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh, vi\u00eam ph\u1ed5i th\u00f9y v\u00e0 vi\u00eam ph\u1ebf qu\u1ea3n ph\u1ed5i, thu\u1ed1c n\u00e0y c\u0169ng r\u1ea5t hay \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 l\u00e0 s\u1ef1 l\u1ef1a ch\u1ecdn \u0111\u1ea7u ti\u00ean.<\/p>\n

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H\u01a1n th\u1ebf n\u1eefa, \u0111\u1ed1i v\u1edbi nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u- sinh d\u1ee5c, ch\u1eb3ng h\u1ea1n nh\u01b0 vi\u00eam b\u00e0ng quang, vi\u00eam ni\u1ec7u \u0111\u1ea1o, vi\u00eam c\u1ea7u th\u1eadn- b\u1ec3 th\u1eadn, nhi\u1ec5m khu\u1ea9n sinh d\u1ee5c n\u1eef v\u00e0 b\u1ec7nh l\u1eadu g\u00e2y ra do vi khu\u1ea9n Neisseria Gonorrhoeae, ph\u1ed1i h\u1ee3p c\u1ee7a d\u1ea1ng b\u00e0o ch\u1ebf Augmentin c\u1ea3 d\u1ea1ng ti\u00eam v\u00e0 d\u1ea1ng u\u1ed1ng \u0111\u1ec1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn.<\/p>\n

Ngo\u00e0i ra, \u0111\u1ed1i v\u1edbi nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m, nhi\u1ec5m khu\u1ea9n x\u01b0\u01a1ng v\u00e0 kh\u1edbp, ch\u1eb3ng h\u1ea1n nh\u01b0 vi\u00eam t\u1ee7y x\u01b0\u01a1ng, th\u01b0\u1eddng ph\u1ea3i \u0111i\u1ec1u tr\u1ecb trong th\u1eddi gian d\u00e0i. C\u00e1c lo\u1ea1i nhi\u1ec5m khu\u1ea9n kh\u00e1c, nh\u01b0 nhi\u1ec5m khu\u1ea9n sau n\u1ea1o thai, s\u1ea3y thai, nhi\u1ec5m khu\u1ea9n trong \u1ed5 b\u1ee5ng, s\u1eed d\u1ee5ng Augmentin c\u0169ng \u0111\u1ec1u mang l\u1ea1i hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb r\u1ea5t t\u1ed1t.<\/p>\n

Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c kh\u00e1ng sinh d\u1ea1ng ph\u1ed1i h\u1ee3p 2 ho\u1ea1t ch\u1ea5t nh\u01b0 Augmentin s\u1ebd kh\u00e1c nhau t\u00f9y thu\u1ed9c v\u00e0o tu\u1ed5i t\u00e1c, c\u00e2n n\u1eb7ng, t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u00e0 kh\u1ea3 n\u0103ng \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a b\u1ec7nh nh\u00e2n. Tuy nhi\u00ean, sau khi d\u00f9ng m\u1ed9t li\u1ec1u Augmentin, th\u00ec li\u1ec1u th\u1ee9 hai trong ng\u00e0y n\u00ean c\u00e1ch li\u1ec1u th\u1ee9 nh\u1ea5t t\u1eeb 8 gi\u1edd \u0111\u1ebfn 12 gi\u1edd. \u0110\u1ec3 t\u1ed1i \u0111a h\u00f3a hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb, n\u00ean d\u00f9ng thu\u1ed1c kh\u00e1ng sinh Augmentin v\u00e0o nh\u1eefng kho\u1ea3ng th\u1eddi gian c\u00e1ch \u0111\u1ec1u nhau v\u00e0 c\u00f9ng m\u1ed9t th\u1eddi \u0111i\u1ec3m m\u1ed7i ng\u00e0y.<\/p>\n

B\u1ec7nh nh\u00e2n c\u1ea7n ph\u1ea3i tu\u00e2n th\u1ee7 li\u1ec1u \u0111\u01b0\u1ee3c k\u00ea trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u1ea3i d\u00f9ng thu\u1ed1c \u0111\u1ee7 s\u1ed1 ng\u00e0y quy \u0111\u1ecbnh, v\u00ec vi\u1ec7c ng\u1eebng thu\u1ed1c qu\u00e1 s\u1edbm c\u00f3 th\u1ec3 l\u00e0m m\u1ea5t \u0111i t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c, khi\u1ebfn cho vi khu\u1ea9n ti\u1ebfp t\u1ee5c ph\u00e1t tri\u1ec3n, d\u1eabn \u0111\u1ebfn nhi\u1ec5m tr\u00f9ng t\u00e1i ph\u00e1t v\u00e0 g\u00e2y vi khu\u1ea9n nh\u1eddn thu\u1ed1c.<\/p>\n

V\u00ec v\u1eady, s\u1ea3n ph\u1ea9m kh\u00e1ng sinh n\u00e0y th\u01b0\u1eddng \u0111\u00f3ng g\u00f3i quy c\u00e1ch h\u1ed9p c\u00f3 14 vi\u00ean\u00a0(2 v\u1ec9, m\u1ed7i v\u1ec9 7 vi\u00ean \u0111\u1ec3 d\u00f9ng cho 7 ng\u00e0y, m\u1ed7i ng\u00e0y 2 vi\u00ean chia l\u00e0m 2 l\u1ea7n). \u0110\u00e2y l\u00e0 li\u1ec1u khuy\u1ebfn c\u00e1o cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em tr\u00ean 12 tu\u1ed5i. N\u1ebfu c\u00f3 d\u1ea5u hi\u1ec7u d\u1ecb \u1ee9ng v\u1edbi Augmentin, b\u1ec7nh nh\u00e2n c\u1ea7n ng\u1eebng d\u00f9ng thu\u1ed1c, t\u00e1i kh\u00e1m v\u00e0 tr\u00ecnh b\u00e0y r\u00f5 v\u1edbi b\u00e1c s\u0129 \u0111\u1ec3 \u0111\u01b0\u1ee3c \u0111\u1ed5i sang m\u1ed9t thu\u1ed1c kh\u00e1c ph\u00f9 h\u1ee3p h\u01a1n, tr\u00e1nh nh\u1eefng h\u1eadu qu\u1ea3 nghi\u00eam tr\u1ecdng c\u00f3 th\u1ec3 x\u1ea3y ra.<\/p>\n

C\u00e1c thu\u1ed1c lo\u1ea1i kh\u00e1ng sinh k\u1ebft h\u1ee3p \u0111\u1ed3ng th\u1eddi ch\u1ee9a Amoxicillin v\u00e0 Acid Clavulanic c\u00f3 t\u00e1c d\u1ee5ng t\u1ed1t h\u01a1n so v\u1edbi d\u00f9ng Amoxicillin \u0111\u1ed9c l\u1eadp. C\u00e1c tr\u01b0\u1eddng h\u1ee3p vi\u00eam m\u0169i h\u1ecdng n\u1eb7ng, k\u00e9o d\u00e0i v\u00e0 c\u00f3 nguy c\u01a1 bi\u1ebfn ch\u1ee9ng cao, b\u00e1c s\u0129 s\u1ebd \u01b0u ti\u00ean ch\u1ec9 \u0111\u1ecbnh Augmentin h\u01a1n l\u00e0 Amoxicillin. Tuy nhi\u00ean, v\u1edbi c\u00f4ng th\u1ee9c b\u00e0o ch\u1ebf d\u1ea1ng vi\u00ean h\u00e0m l\u01b0\u1ee3ng 1 gam, bao g\u1ed3m 875 gam kh\u00e1ng sinh Amoxicillin v\u00e0 125 gam mu\u1ed1i Natri c\u1ee7a Acid Clavulanic, \u0111\u00e2y l\u00e0 d\u1ea1ng vi\u00ean thu\u1ed1c l\u1edbn g\u00e2y kh\u00f3 nu\u1ed1t. B\u1ec7nh nh\u00e2n c\u1ea7n u\u1ed1ng thu\u1ed1c v\u1edbi nhi\u1ec1u n\u01b0\u1edbc, m\u1ed9t c\u1ed1c kho\u00e3ng 200ml \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n nu\u1ed1t thu\u1ed1c. D\u1ea1ng b\u00e0o ch\u1ebf n\u00e0y c\u0169ng g\u00e2y kh\u00f3 ch\u1ecbu cho b\u1ee5ng v\u00e0 h\u1ec7 ti\u00eau h\u00f3a nhi\u1ec1u h\u01a1n so v\u1edbi s\u1eed d\u1ee5ng \u0111\u01a1n \u0111\u1ed9c m\u00ecnh Amoxicillin.<\/p>\n

ThS.L\u00ea Qu\u1ed1c Th\u1ecbnh – Gi\u1ea3ng vi\u00ean Khoa D\u01b0\u1ee3c<\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Khi h\u1ecdc th\u1ef1c h\u00e0nh b\u00e1n thu\u1ed1c, Sinh vi\u00ean Khoa D\u01b0\u1ee3c r\u1ea5t hay g\u1eb7p lo\u1ea1i thu\u1ed1c Kh\u00e1ng sinh n\u00e0y trong nhi\u1ec1u t\u00ecnh hu\u1ed1ng d\u00f9ng thu\u1ed1c, k\u1ec3 c\u1ea3 c\u00e1c B\u1ec7nh \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, B\u1ec7nh \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, b\u1ec7nh \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u. 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